Can I Mix Huperzine a With MK 677? [Explained]

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Written By David Falcone

Mixing two drugs is quite dangerous because most of the time it has a negative reaction. So, before mixing it, you have to know about every detail of the two drugs. Drug reactions harm your body so much that it won’t recover quickly. 

Are you curious about how huperzine A mix with MK 677?

No, you cannot combine huperzine with MK 677. Every medication, as we all know, serves a particular function. Similarly, huperzine A and MK 677. So, if you combine these two, major harm can result. Certain medications can only be combined with huperzine A.

In this portion, I talked about it briefly. Let’s go through everything in more depth so you get the whole picture. It will save you from serious harm.

What is Huperzine A and MK677? 

huperzine a with mk 677

Huperzine A is a plant chemical produced from Chinese club moss (Huperzia Serrata). Huperzine A, a dietary supplement, is commonly marketed as a therapy for Alzheimer’s disease.

Huperzine A has been discovered to work as a cholinesterase inhibitor. It is a type of drug used to halt the breakdown of acetylcholine in alternative medicine. It is also a chemical essential to learning and memory.

In addition to being used to treat Alzheimer’s disease, huperzine A can improve learning and memory. It also guards against age-related cognitive impairment.

Furthermore, huperzine A is occasionally used to enhance energy and alertness, and to battle depression. It can also help treat myasthenia gravis, an autoimmune illness affecting the muscles. The research, however, is restricted.

On the other hand, Ibutamoren (MK-677) is a ghrelin channel agonist and growth hormone secretor. It boosts GH and IGF-1 endogenous secretion. A growth hormone secretagogue is basically a chemical in your body. It instructs the endocrine system to emit more growth hormones inside.

MK-677 is orally bioavailable, which means it may be taken orally (no injections needed). To date, no effective orally bioavailable substitutes for synthetic human growth hormone injections have been identified.

It is non-steroidal, like SARMs, but contrary to popular misconception. MK-677 is not a SARM in any way, despite being usually grouped with them. MK-677 has no effect on natural testosterone levels or hormone production. Sometimes reduce the bloat also

Huperzine A’s 4 Effectiveness & Usage 

Huperzine A’s 4 Effectiveness & Usage 

Here we will talk about the effectiveness and uses of huperzine A. You will take it, and it will be beneficial for your health. Let’s discuss that effectiveness. 

1. Dementia

According to some studies, you can take huperzine A orally for up to 8 weeks. It may enhance memory, brain abilities, and behavior in patients with Alzheimer’s disease or dementia. Huperzine A’s long-term consequences in patients with these diseases are unknown.

2. Memory

According to several studies, you can ingest huperzine A orally for four weeks. It enhances the memory of older children and teens who complain of memory issues.

3. Mental Illness

According to preliminary studies, you can ingest huperzine A orally for 12 weeks.  It may enhance memory in people with modest cognitive (mental) impairment.

4. Muscular Disturbance

Myasthenia gravis disorder is a muscle condition. Preliminary research indicates that administering huperzine A intramuscularly for 10 days. It may lessen muscle weakness in people with myasthenia gravis. It may also have the same or longer-lasting effects as intramuscular neostigmine.

Huperzine A Warnings and Precautions

Huperzine A Warnings and Precautions

Above, we talked about the benefits and uses of huperzine. So now we will talk about the opposite reason. It will make you more careful and save you from big problems. Here are all the warnings and precautions about Huperzine A. 

1. Breastfeeding and Pregnancy

There is inadequate trustworthy data to decide if using huperzine A while pregnant or nursing is safe. To be on the safe side, please try to avoid utilizing it.

2. Children

Huperzine A may be safe in children if given orally for less than one month.

3. Slow Heartbeat/Cardiac Conditions:

Huperzine A has the ability to slow the heart rate. People with sluggish heart rates or other cardiac issues may find this difficult. Contact your doctor before taking huperzine A if you have heart trouble.

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4. Epilepsy (seizure disorder):

Huperzine A may aggravate epilepsy. If you have a seizure disorder. Such as epilepsy, see your doctor before taking huperzine.

5. Blockage of the gastrointestinal (GI) tract:

Huperzine A may aggravate GI obstruction. If you have a GI tract obstruction, see your doctor before using huperzine A.

6. Ulcers in the Stomach:

Huperzine A may aggravate stomach ulcers. If you have stomach ulcers, see your doctor before using huperzine A.

7. Lung Diseases:

Huperzine A has the potential to aggravate asthma or chronic obstructive lung disease (COPD). Consult your doctor before using huperzine A if you have asthma or COPD.

8. Urinary Tract Obstruction:

Huperzine A may aggravate urinary tract obstruction. If you have a urinary tract obstruction, see your doctor before using huperzine A.

Huperzine A Interactions with Drugs

Huperzine A Interactions with Drugs

Every drug has different types of side effects. But when you mix it together without knowing everything properly, it will cause harm. If you want to mix huperzine A with MK677, just like deca and test. But you can’t mix MK 677 with huperzine A. 

Huperzine A interacts with drying medicines (anticholinergic drugs). Huperzine A can raise levels of acetylcholine in the body.  Acetylcholine is essential for numerous bodily activities. 

Anticholinergic drugs work by preventing the effects of acetylcholine in the body. Anticholinergic medicines may be less effective if you use huperzine A.

Huperzine A can raise levels of acetylcholine in the body. Some drugs used to treat glaucoma, Alzheimer’s disease, and other disorders raise acetylcholine levels. Consuming huperzine A with these drugs may increase the likelihood of negative effects.

Adverse Effects

Cholinergic adverse effects were seen in the clinical studies conducted. It included hyperactivity, nasal blockage, nausea, vomiting, diarrhoea, sleeplessness, anxiety, dizziness, thirst, and constipation. Cardiovascular ischemia and arrhythmia were found in the ECG pattern.


Acute poisoning symptoms include muscle tremors, drooling, tears, increased respiratory secretions, and incontinence. In rats, the acute oral median fatal dosage of huperzine A was 4.6 mg/kg, whereas the intravenous dose was 0.63 mg.

In one toxicological study, serum aminotransferases were shown to be elevated. After 180 days of treatment, no pathological alterations were observed. There were no indications in histological investigations of the liver, kidney, heart, lungs, or brain. Also, no mutagenicity or teratogenicity was found in rodent experiments.

FAQ’s :

  • MK-677 might cause cardiac problems?

MK-677 appears to be well tolerated in available trials. Nonetheless, there is a bias toward decreasing insulin sensitivity. MK-677 did not have any harmful side effects. MK-677, on the other hand, exhibited an unsatisfactory safety profile in those with congestive heart failure.

  • Does MK-677 raise prolactin levels?

Transaminase increases were not observed in any subjects receiving MK-677 in the 2- or 9-week investigations. Finally, a mean rise from baseline serum prolactin of 27% was seen in the 9-week trial. Although, post-treatment levels remained within the physiologic range.

  • Is MK-677 a male hormone?

Ibutamoren, commonly known as MK-677, is one of the most potent and effective SARMs available. For those who are unaware, SARMs are selective estrogen receptor frequency modulators. These medicines can only interact with androgen receptors in the muscle.

  • Does MK-677 have anti-aging properties?

MK-677 has muscle-building capabilities, reduces muscle wasting, improves bone density, improves sleep, and has anti-aging characteristics. It may also have nootropic properties and be useful in treating growth hormone deficits.

Wrap up 

Are you clear about it now? I guess it will clear up all your doubts about the Huperzine A mix with MK677. Before taking or mixing any drug, you have to check the negative reactions and side effects. 

It is a mandatory process. Because when drugs react negatively in the body it will leave big harm for the future. If you can consult a doctor, it would be best. 

I hope you like the article. Take care of yourself and stay safe.

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