Accadrine vs Ostarine: Which One Is the Better Sarm?

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Written By David Falcone

Accadrine and ostarine are both SARMs and share some similarities in terms of overall effects. That includes muscle protection, mild anabolic response, minimal androgenic effect and so on. 

Then what’s the difference? What makes you question accadrine vs ostarine?

Accadrine, commonly AC-262, is a SARM for androgen replacement therapy. Bodybuilding enthusiasts and athletes intake Ostarine to improve lean body mass. Accadrine is active in affecting the prostate whereas ostarine is mild. Accadrine research is completely animal-based but ostarine is human-based. 

Among many SARM, ostarine is a widely used drug with minimal androgenic side effects. Accadrine is pretty much similar and differs in effectiveness. 

Now, which one do you have to choose between Accadrine and Ostarine? Here we have compared the features of Accadrine and Ostarine. This will help you choose the perfect SARM.

So, let’s get started!

Accadrine vs Ostarine: Short Comparison

Accadrine vs Ostarine Short Comparison

Accadrine and ostarine are compounds that belong to SARM (Selective Androgen Receptor Modulator). Accadrine was created to deal with degenerative cognitive disorders, while Ostarine was for AIDS or cancer ailments. 

Again, research on accadrine has been done on animals but, ostarine’s research is completed on humans. Accadrinne is a partial agonist and ostarine is a full agonist. So, the potency of accadrine is lesser than ostarine. 

Their dosing cycle also differs in weeks. Although ostarine is taken in mild power, it’s more suppressive. That’s why its cycle is for 2-3 weeks more than accadrine.

Moreover, there are other noticeable differences between accadrine and ostarine. They are discussed below-

PotencyPartial agonistFull agonist
Anabolic responseLowerHigher
Dosing & cycle10 weeks (for dose 10-30 mg)12-16 weeks (for dose 25 mg)
Stack Andarine or Ligandrol.With Andarine
PCTNot mandatoryRebirth

Technically, accadrine and ostarine have some similarities between them as both are SARMs. But based on research, these above-mentioned facts create slight differences between them. 

Let’s have an extended comparison between them.

Accadrine vs Ostarine: Extended Comparison

Accadrine vs Ostarine

In a short comparison I talked briefly about the different features of accadrine and ostarine. This information is quite vague to know the reasons behind the differences. 

For this, we need to have a detailed comparison of the features.

Let’s get started!

1. Potency

Accradine is a partial agonist for which its potency is less. Because partial agonists have lower efficacy and produce sub-maximal activation. 

Although it occupies the total receptor population, a partial agonist cannot produce the maximal response. Even when concentration is applied.

On the other hand, Ostarine is a full agonist. Because of its higher efficacy, it can produce a full response unlike partial. It occupies a relatively low proportion of receptors. Yet, as it is a full agonist its potency is more.

So, ostarine wins here!

2. Anabolic Response

Ostarine is famous for being the top priority for people who want to grow muscle mass. It’s a full agonist of androgen receptors that exerts an anabolic effect on the body.

This might cross your mind, does Ostarine make you bigger? The answer is in the affirmative.

Ostarine will make you bigger or bulkier in a 6-8 week cycle. You may gain approximately 5-7 pounds or more in 6-8 weeks.

The higher anabolic effect makes ostarine suitable for beginner’s chemical research. But in terms of muscle building, the anabolic effect of ostarine is mild. Accadrine finds a similarity here.

Accadrine’s anabolic response is quite minimal and has few chances of androgenic side effects. Keeping in mind that a proper dose is strictly necessary. But overall, its anabolic response is lower in binding affinity.

The anabolic response of the androgen receptor of accadrine is lower in comparison to ostarine. Although, the anabolic response of both ostarine and accadrine is mild to androgenic side effects.

Therefore, accadrine and ostarine make a tie here with their similar overall anabolic effect.

3. Dosing And Cycle

Not a lot of research is done regarding AC-262 or Accadrine. It’s anecdotal and not very effective like other SARMs. 

So, when you take Accadrine for bodybuilding purposes, make sure to take the perfect dose. Its dosage is really different from taking the 400mg test cycle

Take 10-30 mg every day within a cycle of 10 weeks. Though the cycle will be dependent on the dose, the higher the dose, the more aggressive the lockdown.

Here you may ask about ac-262 sarm side effects. Well, of course, Accadrine has side effects. You’ll have mild side effects at lower doses and suppress testosterone production at higher doses.

The mentionable androgenic side effects are-

  • Drop in testosterone levels.
  • Fatigue
  • Exhaustion, nausea, vomiting
  • Headache

No major side effects are observed while you are on AC-262. 

Ostarine, according to medical research, has a half-life of 24 hours. As per scientific reasoning, there is no limit to the appropriate amount of dosage. 

Yet a cycle of 12-16 weeks should be maintained while taking a 3 mg dose every day.  Bottom line, misuse of ostarine can be proved dangerous. 

Besides, you may be curious about ostarine sarm side effects. Some noticeable side effects are-

  • Liver damage
  • Heart disease
  • Heart attack
  • Increase in testosterone

To avoid such major effects proper dose of medication is necessary. In rare cases, Ostarine can cause gyno, so you need to take more precautions. 

4. Stack

It is possible to stack Andarine or Ligandrol with accadrine. This helps in cutting while keeping the side effects minimal.  Added to that, Ligandrol includes ingredients that help in the process of muscle recovery.

On the other hand, andarine and ostarine make the best stack for cutting. This also helps in keeping you strong and maintaining your size. Ostarine can be stacked with cardarine too. That’ll increase physical performance.

However, besides cutting, Ostarine and Andarine promote hair restoration. This is due to changes in testosterone balance. 

I can recommend some good supplements for hair growth you may take with Ostarine or Accadrine. 

TRICHOFOLAll natural Samurai formula that rejuvenates your hair follicles and gives you back your lost hair, without drugs, dangerous surgery or expensive therapies.
RESTOLINRestolin is a natural hair restoration formula which consists of amazing vitamins and plants.

As it is anecdotal, you may ask about the authenticity of does Ostarine produce DHT?

Well yes, research revealed that SARMs can outcompete Dihydrotestosterone (DHT) which benefits your hairline.

5. PCT (Post Cycle Therapy)

Post Cycle Therapy is highly recommended when it comes to taking any supplement. For accadrine, though it is not mandatory. Because it is non-steroidal and causes fewer side effects. 

While taking it in weeks, a gap of 2-3 weeks is recommended. Any PCT supplement is not mandatory.

Meanwhile, it is recommended to take PCT while on Ostarine because Ostarine is suppressive. Rebirth is highly suggested. 

Benefits Of Accadrine And Ostarine

Accadrine or, AC-262 and Ostarine or, MK 2866 are both SARMs. But their benefits are different just like their side effects. For different purposes, they can be used at different times. 

Therefore, to perfectly know the difference you need to know their benefits as well. The necessary results you can get using Ostarine are-

  • Major fat reduction
  • Pumps up testosterone
  • Improves muscle mass
  • Faster recovery
  • Higher bone density
  • Improve lean body mass.
  • New good results in curing breast cancer, and loss of bladder control.

Now, what are the benefits of accadrine for which you should buy it?

The necessary results you can get using accadrine are-

  • Increase strength, and bone density
  • Increase endurance
  • Increase muscle density, size and definition
  • Sharpens cognitive responses 
  • Fastens recovery

There is another supplement I can recommend that you can use to increase your bone density. 

FLEXOBLISSThis natural supplement can improve the health of your bones and back muscles to keep you flexible and active.

For specific situations, you can consider the benefits of Andarine and Ostarine to use. Besides knowing the benefits, you should reconsider the side effects too. Because just considering the benefits may affect you unexpectedly. 

Accadrine vs Ostarine: Which One Is Better?

Accadrine vs Ostarine Which One Is Better

In terms of overall effects, we can see many similarities and dissimilarities between accadrine and ostarine. Even after the overall discussion, you may not be able to decide which one to choose. 

Ostarine is mildly suppressive even when taken at higher doses. Whereas, accadrine or, AC-262 despite having a poor androgenic or anabolic ratio, is more suppressive. 

Curing breast cancer, the ailment of AIDS, and cancer patients have been the main focus of ostarine. And Accadrine was created for degenerative cognitive disorders like Alzheimer’s. 

Accadrine is used for bone degenerative disorder and cognitive decline disorder. On the other hand, Ostarine is hugely used for burning fat and bodybuilding purposes.

Ostarine increases muscles and accadrine increases strength. 

The side effects of ostarine are less than accadrine, which makes ostarine a better choice.

Final Verdict

Basically, SARMs are agents that stimulate anabolism. Both are SARMs and both behold different features. Considering the mentioned differences you can choose the best SARM in terms of need. 

Accadrine and Ostarine are two SARMs that aren’t steroids and increase strength and muscle mass. 

If you wish to increase your strength then accadrine is good. For muscle mass increase ostarine would be a better choice; keeping side effects and benefits into account.


  • Is Ostarine best for cutting?

Yes, ostarine is best during the cutting phase. While people go through hard diets during the cutting phase, ostarine comes as consolation.

  • Does Ostarine raise testosterone levels?

Yes, ostarine supposedly improves testosterone. Its effective nature regulates the level of body fat.

  • Is Accadrine a steroid?

No, Accadrine is non-steroidal. It’s one of the SARMs which is a partial agonist and also acts as an androgen receptor. 


So, that’s all about accadrine vs ostarine. 

Using any of the SARMs by knowing only the benefits can be harmful. Even ignoring any of it by just knowing the side effects will be problematic too. I have elaborately discussed these in this article. 

Hope you have got the answer to all your questions. Either way, let me know if you’ve any more queries. Enjoy!

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